Exploiting Hydrophobic Amino Acid Scanning to Develop Cyclic Peptide Inhibitors of the SARS-CoV-2 Main Protease with Antiviral Activity

peptide inhibitor designSARS-CoV-2cyclic peptidesmolecular dynamics
Written By Dana Matthews

Katriona Harrison, Patrick W. Carlos, Sven Ullrich, Anupriya Aggarwal, Jason Johansen‐Leete, Vishnu Mini Sasi, Isabel Barter, Joshua WC. Maxwell, Max J. Bedding, Mark Larance, Stuart Turville, Alexander Norman, Colin J. Jackson, Christoph Nitsche, and Richard J. Payne*

Exploiting Hydrophobic Amino Acid Scanning to Develop Cyclic Peptide Inhibitors of the SARS-CoV-2 Main Protease with Antiviral Activity

Chemistry – A European Journal, 2024

Dana Matthews
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Increasing the Soluble Expression and Whole-Cell Activity of the Plastic-Degrading Enzyme MHETase through Consensus Design
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Conformational Preferences of the Non-Canonical Amino Acids (2S,4S)-5-Fluoroleucine, (2S,4R)-5-Fluoroleucine, and 5,5'-Difluoroleucine in a Protein