An Engineered Biarylitide Cross-Linking P450 from RiPP Biosynthesis Generates Alternative Cyclic Peptides
Maxine Treisman, Laura Coe, Yongwei Zhao, Vishnu Mini Sasi, Jemma Gullick, Mathias H. Hansen, Aviva Ly, Victor Leichthammer, Caroline Hess, Daniel L. Machell, Ralf B. Schittenhelm, Joel Hooper, Colin J. Jackson, Julien Tailhades, James J. De Voss* and Max J. Cryle*
Organic Letters, 2024
Structural Insights into a Side Chain Cross-Linking Biarylitide P450 from RiPP Biosynthesis
Mathias H. Hansen*, Angus Keto, Maxine Treisman, Vishnu Mini Sasi, Laura Coe, Yongwei Zhao, Leo Padva, Caroline Hess, Victor Leichthammer, Daniel L. Machell, Ralf B. Schittenhelm, Colin J. Jackson, Julien Tailhades, Max Crüsemann, James J. De Voss, Elizabeth H. Krenske and Max J. Cryle*
Structural Insights into a Side Chain Cross-Linking Biarylitide P450 from RiPP Biosynthesis
ACS Catalysis, 2024
P450-mediated dehydrotyrosine formation during WS9326 biosynthesis proceeds via dehydrogenation of a specific acylated dipeptide substrate
Songya Zhang, Lin Zhang, Anja Greule, Julien Tailhades, Edward Marschall, Panward Prasongpholchai, Daniel J. Leng, Jingfan Zhang, Jing Zhu, Joe A. Kaczmarski, Ralf B. Schittenhelm, Oliver Einsle, Colin J. Jackson, Fabrizio Alberti, Andreas Bechthold, Youming Zhang, Manuela Tosin*, Tong Si*, and Max J. Cryle*
Acta Pharmaceutica Sinica B, 2023
Complex Inhibitory Mechanism of Glycomimetics with Heparanase
Cassidy Whitefield, Yen Vo, Brett D Schwartz, Caryn Hepburn, F Hafna Ahmed, Hideki Onagi, Martin G Banwell, Keats Nelms, Lara R Malins and Colin J Jackson
Complex Inhibitory Mechanism of Glycomimetics with Heparanase
Biochemistry, 2023
A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein
Vito Thijssen, Daniel L. Hurdiss, Oliver J. Debski-Antoniak, Matthew A. Spence, Charlotte Franck, Alexander Norman, Anupriya Aggarwal, Nadia J. Mokiem, David A.A. van Dongen, Stein W Vermeir, Minglong Liu, Wentao Li, Marianthi Chatziandreou, Tim Donselaar, Wenjuan Du, Ieva Drulyte, Berend-Jan Bosch, Joost Snijder, Stuart G. Turville, Richard J. Payne, Colin J. Jackson, Frank J.M. van Kuppeveld*, Seino A.K. Jongkees*
A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein
Proceedings of the National Academy of Sciences, 2023
Asymmetric Ene-Reduction by F420-Dependent Oxidoreductases B (FDOR-B) from Mycobacterium smegmatis
Suk Woo Kang, James Antoney, David W Lupton, Robert Speight, Colin Scott and Colin J Jackson
Asymmetric Ene-Reduction by F420-Dependent Oxidoreductases B (FDOR-B) from Mycobacterium smegmatis
ChemBioChem, 2023
